Careers at Roche

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Who We Are At Roche Diagnostics Solutions (RDS) , our mission is clear: to diagnose earlier, develop faster, and personalize treatment because every patient is unique. Within Computational Science & Informatics (CSI) , we are the bridge between our origin and our future, shaping the next era of human health through precise, data-driven diagnostics and precision medicine. We excel in delivering rigorous, clinically actionable data analysis across our diagnostics portfolio, believing that advancing computational methods and informatics solutions is essential to harnessing dynamic human health data. By listening closely to patients and physicians, and leveraging digitization and cutting-edge technologies, we work collaboratively to turn insights into impact. This shared spirit creates an environment where ideas grow, new approaches are trialed, and competitive products reach patients faster—ultimately realizing the DIA 10-year vision and our One Roche ambitions so that everyone can access personalized healthcare solutions. The Opportunity We are looking for an experienced Backend Python Engineer/Scrum Master to build robust, scalable APIs and services that power our digital products in the life sciences sector. Working closely with our Frontend/UX team and Data Scientists, you will design the backend infrastructure required to process, manage, and serve complex bioinformatics and machine learning data. In this highly collaborative role, you will tackle challenges ranging from optimizing database queries for massive datasets to architecting cloud-native solutions on AWS. We value engineers who are comfortable exploring complex data structures, establishing clean API boundaries, and ensuring high reliability as we scale our platforms to support critical scientific innovation. Duties and responsibilities Design, build, and maintain high-performance, asynchronous backend services and robust RESTful APIs. Architect, deploy, and manage scalable and secure cloud infrastructure, utilizing Infrastructure as Code (IaC) principles. Design efficient database schemas, manage complex data relationships, execute seamless migrations, and ensure performant query optimization for massive datasets. Build and maintain data pipelines to ingest, normalize, and process large volumes of structured and unstructured scientific and bioinformatics data. Champion engineering excellence by writing clean, testable code, implementing comprehensive automated testing, and maintaining reliable CI/CD pipelines. Partner directly with the UX/Frontend team to establish seamless API integrations, and collaborate with Data Scientists to bring machine learning models into production workflows. Scrum Master Responsibilities (20%) Act as a servant leader for the development team, applying Scrum principles to facilitate progress, resolve conflicts, and increase transparency. Empower the team by removing blockers and applying proven Agile techniques to drive continuous improvement. What You Bring The Must-Haves 5+ years of software engineering experience, with Python as your primary language. Strong software engineering fundamentals, including robust API design and experience building and scaling RESTful systems. Solid understanding of relational databases, data modeling, schema migrations, and query optimization. Proven experience building, deploying, and managing scalable infrastructure in cloud environments, ideally utilizing Infrastructure as Code (IaC). A strong focus on code quality, automated testing, and maintainability within CI/CD pipelines. Demonstrated ability to make progress in ambiguous environments, taking ownership of problems end-to-end—from understanding user needs to shipping production-ready solutions. Tech Stack Alignment: Hands-on experience with, or a strong foundation to quickly adapt to, our core stack: FastAPI, PostgreSQL, SQLAlchemy, Alembic, AWS (S3, Aurora, Fargate, Lambda, CDK), pytest, and NumPy. The Nice-to-Haves: Domain knowledge or a strong interest in the life sciences sector, specifically Sequencing, PCR, Bioinformatics, or digital healthcare. Direct experience working with AWS HealthOmics or building data pipelines for genomic/biological data. Background in data-heavy or AI-integrated product architectures, including an interest in how AI/ML systems behave in production. Previous experience working within large, globally distributed enterprise environments (e.g., Pharma, MedTech). Scrum Master Skills First level Scrum Master certification (CSM, PSM I) Experience playing the Scrum Master role for at least two years for a software development team that was diligently applying Scrum principles, practices, and theory. Good skills and knowledge of servant leadership, facilitation, situational awareness, conflict resolution, continual improvement, empowerment, and increasing transparency Knowledge of numerous well documented patterns and techniques for filling in the intentional gaps left in the Scrum approach At Roche, you’ll thrive in a culture that values different perspectives and creates a place of belonging, where we challenge ourselves to excel and achieve strong results, together. Let’s create a healthier, brighter future for all. * This is an on-site position and no relocation assistance is provided. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position The Pharma Technical Operations Global MSAT and Engineering function (PTT) is undergoing a massive, multi-site modernization initiative. We lead seamless industrialization and technical management across our global landscape—owning product and process robustness, efficiency, and reliability. By integrating scalable manufacturing technologies, PTT introduces innovative, efficient, and sustainable equipment to shape Roche's manufacturing network of the future. The Opportunity As the Technology Deployment Manager – Robotics & Automation, you identify, develop, and integrate state-of-the-art robotics into our commercial manufacturing architecture. By deploying innovations—including Autonomous Mobile Robots (AMRs), cobots, automated process and test equipment, and AI-driven material handling, you align technological advancements with operational excellence to ensure our network remains robust, flexible, and scalable. End-to-End Project Execution: Lead complex robotics deployment projects within GxP-regulated commercial manufacturing and logistics environments from concept through qualification. Proof-of-Concept & Pilot Scale: Drive feasibility assessments, PoC trials, and site pilot implementations to validate technical readiness and establish clear business cases before network-wide scaling. Strategy Translation: Convert global technology roadmaps for robotics, flexible automation, and mechatronic systems into site-level execution plans aligned with broader business objectives. Standards Governance: Partner with Strategy & Standards and Fleet Program Leads to establish, embed, and validate global hardware, software, safety interlock, control architecture, and cybersecurity standards. Cross-Functional Leadership: Act as the primary execution liaison connecting Pharma Technical Development, global MSAT, Site Engineering, IT/OT, Quality/Compliance, and Site Manufacturing Operations. IT/OT System Integration: Collaborate with automation and digital teams to seamlessly integrate robotic controllers, fleet management systems, and computer vision into site MES, SCADA, and ERP architectures. Vendor Lifecycle Management: Manage robotics and automation vendors end-to-end—including technical evaluation, RFP development, contract engagement, design reviews (FAT/SAT), and performance monitoring. Who You Are You are a pragmatic innovator with deep technical know-how and hands-on expertise deploying robotics within complex GxP environments. You are driven to solve critical site operational challenges using scalable technology. Bachelor’s, Master’s, or Ph.D. in Robotics Engineering, Mechatronics, Electrical/Mechanical Engineering, Automation Engineering, or a related technical discipline. Preferred: Business Administration (e.g., MBA), Change Management, or Systems Engineering certifications. 6+ years of hands-on experience in robotics integration, complex automation deployment, or manufacturing engineering within pharmaceutical, biotech, or other highly regulated industries. Direct involvement across major Capital Expenditure (CAPEX) project lifecycles, including Commissioning, Qualification, and Validation (CQV). Proven ability to influence, align, and lead multi-site project teams without direct hierarchical authority. Solid grasp of IT/OT layers (SCADA/MES) and basic data processing/coding literacy (e.g., Python, SQL) to evaluate system performance metrics, as well as hands-on experience deploying assembly and packaging automation within Device, Packaging & Distribution environments. Direct expertise with high-speed discrete robotics, collaborative robots (cobots), track-and-trace serialization, auto-injector assembly, or robotic palletizing. Ready to take the next step? We'd love to hear from you. Apply now to explore this exciting opportunity! Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Software Developer Roche Digital Technology (RDT) is where innovation meets purpose. As a global team at the heart of Roche, we are a community of business-minded technologists committed to help shape tomorrow’s digital future of healthcare. Our mission is to power Roche through cutting-edge digital technologies, harnessing the potential of artificial intelligence, data, and scalable tech innovations. Driven by purpose and passion, we’re building a future where digital is a core strength across all of Roche, enabling smarter ways of working, unlocking human potential, and driving breakthroughs that truly matter for millions of patients around the world. At Roche, we offer a hybrid work model that combines flexibility with in-person collaboration. For now, we require our employees to be in our offices on average two days per week . The specific office days may vary depending on business needs, such as workshops, conferences, town halls, team meetings, and other collaborative events. As a Software Developer, you act as a seasoned expert who takes ownership of tasks and drives quality. You will challenge the status quo, foster collaboration and mentorship, and design complex software solutions utilizing strong full-stack expertise. By possessing a deep understanding of the broader technical landscape, you will improve the entire software delivery process, proactively addressing technical debt and architectural challenges while aligning your efforts with global organizational strategies. The opportunity: Agentic Architecture: Design, deploy, and scale multi-agent orchestration systems and autonomous workflows using cutting-edge frameworks. Advanced RAG Pipelines: Build and optimize advanced retrieval-augmented generation (RAG) pipelines over massive, heterogeneous datasets (structured and unstructured). State & Memory Management: Implement robust state management, short/long-term memory systems, and self-correction/reflection loops within agent networks. Evaluation & Guardrails: Create and implement robust evaluation metrics, observability pipelines, and guardrails for content quality, hallucination reduction, bias mitigation, and safety standards. Performance Optimization: Monitor and optimize AI inference cost, latency, throughput, token usage, and overall system reliability. Security & Access Control: Implement robust access controls, data encryption, user authentication, and prompt injection mitigation across all LLM workflows. Collaboration & Best Practices: Document and share reusable agent patterns, prompt libraries, and engineering components across cross-functional technical teams. End-to-End Pipeline Delivery: Independently leads the design, build, and maintenance of scalable data pipelines, managing specific data engineering projects autonomously from inception to deployment. Performance Optimization & Problem Solving: Solves complex data ingestion and processing challenges, actively optimizing data flows to enhance overall system performance and reliability. Stakeholder Alignment & Integration: Partners directly with business units and data scientists to understand data requirements, effectively bridging technical execution with non-technical business needs. Strategic Infrastructure Impact: Owns large-scale data engineering initiatives, implementing robust strategies that significantly modernize and strengthen the organization’s data infrastructure. Complex Data Integration: Manages large, intricate data ecosystems by seamlessly integrating multiple diverse data sources to ensure efficient, secure cross-platform data flows. Impact/Strategy: Acts as a technical mentor and aligns development plans with the global strategy. Gets involved in initiatives and tasks reaching outside of regular project scope, gives speeches, shares knowledge in organizational events (e.g., DevOps Days, Tech Talk), and engages in the organization of knowledge-sharing events. Who you are: Education & Experience: Bachelor’s or Master’s degree in Computer Science, Software Engineering, or related technical field (Required), along with 4+ years of professional software development experience (Required). Technical Proficiency: Strong full-stack expertise with hands-on experience in LLM frameworks, agentic architectures, and advanced RAG pipelines (Required); familiarity with cloud services and DevOps practices (Preferred). Problem Solving & Ownership: Proactive self-starter who takes ownership of complex architectural challenges, tackles technical debt, and drives end-to-end software delivery (Required). Collaboration & Mentorship: Strong communicator who enjoys mentoring peers, sharing knowledge across cross-functional teams, and bridging technical solutions with business needs (Required). Continuous Improvement: Curious mindset eager to challenge the status quo, adopt emerging AI technologies, and align development practices with global strategies (Required). Additional Qualifications Exceptional communication and collaboration skills , with the proven ability to engage effectively with both technical audiences (like data scientists) and non-technical business stakeholders. Pharma & GxP Compliance: Extensive experience in pharma or biotech, architecting data pipelines that strictly comply with GxP frameworks (GCP/GMP/GVP), data integrity principles, and computer systems validation (CSV). Compliant Data Delivery: Proven capability to build scalable solutions within regulated R&D environments, aligning technical execution with critical Clinical, Regulatory, and Safety milestones. Workflow & Data Optimization: Skilled at identifying bottlenecks, eliminating operational silos, and optimizing fragmented workflows to ensure automated, streamlined solutions. What you get: Salary range 14,175 - 26,325 PLN gross based on the employment contract. Annual bonus payment based on your performance. Dedicated training budget (training, certifications, conferences, diversified career paths etc.). Recharge Fridays (2 Fridays off per quarter available). Take time Program (up to 3 months of leave to use for any purpose). Vacation subsidy available. Flex Location (possibility to perform our work from different places in the world for a certain period of time). Take Time for Charity (additional paid leave of maximum 2 weeks to engage in the charity action of your choice). Private healthcare (LuxMed packages), group life insurance (UNUM) and Multisport. Stock share purchase additions. Yearly sales of company laptops and cars and many more! Apply directly and join us in shaping the future of healthcare. If you feel this offer suits a friend of yours, feel free to share it. Want to know what it’s like to be a part of Roche IT first-hand? Check out our blog! https://careers.roche.com/global/en/we-are-roche ….. The controller of your personal data is Roche Polska Sp. z o.o., ul. Domaniewska 28, 02-672 Warsaw. The data is processed for the purpose of recruitment. You have the right to access your data, rectify it, delete it, limit processing, transfer it and - if processing is based on your consent - withdraw this consent at any time. Contact the Data Protection Officer at: Ochrona.danych@roche.com. More information on the principles of processing your personal data by Roche at the link: https://www.roche.pl/pl/content/klauzula-informacyjna-rekrutacja-en.html Roche Polska sp. z o.o. operates in full compliance with the law and does not tolerate any violations. Roche Polska sp. z o.o. has implemented a Procedure for Reporting Violations of Law. If you wish to report any irregularities related to our activities, all necessary information regarding the reporting process can be found on our website: https://www.roche.pl/kontakt/ochrona-sygnalistow-zglaszanie-naruszen . Compensation & Benefits The expected salary range for this position, based on the primary location of Warsaw Grafit is 170,100.00 PLN - 315,900.00 PLN. Final compensation will be determined by a number of factors, including your skills, experience, qualifications, and location. In addition to base pay, this role may be eligible for a discretionary annual bonus with a target of 15% subject to both individual and company performance. This position also offers an attractive benefits package . Learn more about how we reward our employees at Roche. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Software Developer Roche Digital Technology (RDT) is where innovation meets purpose. As a global team at the heart of Roche, we are a community of business-minded technologists committed to help shape tomorrow’s digital future of healthcare. Our mission is to power Roche through cutting-edge digital technologies, harnessing the potential of artificial intelligence, data, and scalable tech innovations. Driven by purpose and passion, we’re building a future where digital is a core strength across all of Roche, enabling smarter ways of working, unlocking human potential, and driving breakthroughs that truly matter for millions of patients around the world. At Roche, we offer a hybrid work model that combines flexibility with in-person collaboration. For now, we require our employees to be in our offices on average two days per week . The specific office days may vary depending on business needs, such as workshops, conferences, town halls, team meetings, and other collaborative events. As a Software Developer, you act as a seasoned expert who takes ownership of tasks and drives quality. You will challenge the status quo, foster collaboration and mentorship, and design complex software solutions utilizing strong full-stack expertise. By possessing a deep understanding of the broader technical landscape, you will improve the entire software delivery process, proactively addressing technical debt and architectural challenges while aligning your efforts with global organizational strategies. The opportunity: Agentic Architecture: Design, deploy, and scale multi-agent orchestration systems and autonomous workflows using cutting-edge frameworks. Advanced RAG Pipelines: Build and optimize advanced retrieval-augmented generation (RAG) pipelines over massive, heterogeneous datasets (structured and unstructured). State & Memory Management: Implement robust state management, short/long-term memory systems, and self-correction/reflection loops within agent networks. Evaluation & Guardrails: Create and implement robust evaluation metrics, observability pipelines, and guardrails for content quality, hallucination reduction, bias mitigation, and safety standards. Performance Optimization: Monitor and optimize AI inference cost, latency, throughput, token usage, and overall system reliability. Security & Access Control: Implement robust access controls, data encryption, user authentication, and prompt injection mitigation across all LLM workflows. Collaboration & Best Practices: Document and share reusable agent patterns, prompt libraries, and engineering components across cross-functional technical teams. End-to-End Pipeline Delivery: Independently leads the design, build, and maintenance of scalable data pipelines, managing specific data engineering projects autonomously from inception to deployment. Performance Optimization & Problem Solving: Solves complex data ingestion and processing challenges, actively optimizing data flows to enhance overall system performance and reliability. Stakeholder Alignment & Integration: Partners directly with business units and data scientists to understand data requirements, effectively bridging technical execution with non-technical business needs. Strategic Infrastructure Impact: Owns large-scale data engineering initiatives, implementing robust strategies that significantly modernize and strengthen the organization’s data infrastructure. Complex Data Integration: Manages large, intricate data ecosystems by seamlessly integrating multiple diverse data sources to ensure efficient, secure cross-platform data flows. Impact/Strategy: Acts as a technical mentor and aligns development plans with the global strategy. Gets involved in initiatives and tasks reaching outside of regular project scope, gives speeches, shares knowledge in organizational events (e.g., DevOps Days, Tech Talk), and engages in the organization of knowledge-sharing events. Who you are: Education & Experience: Bachelor’s or Master’s degree in Computer Science, Software Engineering, or related technical field (Required), along with 4+ years of professional software development experience (Required). Technical Proficiency: Strong full-stack expertise with hands-on experience in LLM frameworks, agentic architectures, and advanced RAG pipelines (Required); familiarity with cloud services and DevOps practices (Preferred). Problem Solving & Ownership: Proactive self-starter who takes ownership of complex architectural challenges, tackles technical debt, and drives end-to-end software delivery (Required). Collaboration & Mentorship: Strong communicator who enjoys mentoring peers, sharing knowledge across cross-functional teams, and bridging technical solutions with business needs (Required). Continuous Improvement: Curious mindset eager to challenge the status quo, adopt emerging AI technologies, and align development practices with global strategies (Required). Additional Qualifications Exceptional communication and collaboration skills , with the proven ability to engage effectively with both technical audiences (like data scientists) and non-technical business stakeholders. Pharma & GxP Compliance: Extensive experience in pharma or biotech, architecting data pipelines that strictly comply with GxP frameworks (GCP/GMP/GVP), data integrity principles, and computer systems validation (CSV). Compliant Data Delivery: Proven capability to build scalable solutions within regulated R&D environments, aligning technical execution with critical Clinical, Regulatory, and Safety milestones. Workflow & Data Optimization: Skilled at identifying bottlenecks, eliminating operational silos, and optimizing fragmented workflows to ensure automated, streamlined solutions. What you get: Salary range 14,175 - 26,325 PLN gross based on the employment contract. Annual bonus payment based on your performance. Dedicated training budget (training, certifications, conferences, diversified career paths etc.). Recharge Fridays (2 Fridays off per quarter available). Take time Program (up to 3 months of leave to use for any purpose). Vacation subsidy available. Flex Location (possibility to perform our work from different places in the world for a certain period of time). Take Time for Charity (additional paid leave of maximum 2 weeks to engage in the charity action of your choice). Private healthcare (LuxMed packages), group life insurance (UNUM) and Multisport. Stock share purchase additions. Yearly sales of company laptops and cars and many more! Apply directly and join us in shaping the future of healthcare. If you feel this offer suits a friend of yours, feel free to share it. Want to know what it’s like to be a part of Roche IT first-hand? Check out our blog! https://careers.roche.com/global/en/we-are-roche ….. The controller of your personal data is Roche Polska Sp. z o.o., ul. Domaniewska 28, 02-672 Warsaw. The data is processed for the purpose of recruitment. You have the right to access your data, rectify it, delete it, limit processing, transfer it and - if processing is based on your consent - withdraw this consent at any time. Contact the Data Protection Officer at: Ochrona.danych@roche.com. More information on the principles of processing your personal data by Roche at the link: https://www.roche.pl/pl/content/klauzula-informacyjna-rekrutacja-en.html Roche Polska sp. z o.o. operates in full compliance with the law and does not tolerate any violations. Roche Polska sp. z o.o. has implemented a Procedure for Reporting Violations of Law. If you wish to report any irregularities related to our activities, all necessary information regarding the reporting process can be found on our website: https://www.roche.pl/kontakt/ochrona-sygnalistow-zglaszanie-naruszen . Compensation & Benefits The expected salary range for this position, based on the primary location of Warsaw Grafit is 170,100.00 PLN - 315,900.00 PLN. Final compensation will be determined by a number of factors, including your skills, experience, qualifications, and location. In addition to base pay, this role may be eligible for a discretionary annual bonus with a target of 15% subject to both individual and company performance. This position also offers an attractive benefits package . Learn more about how we reward our employees at Roche. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position AI Biology & Translation (AIBT) develops and applies state-of-the-art artificial intelligence to accelerate biomedical discovery across Research and Early Development in Genentech & Roche. We combine advances in foundation models, multimodal machine learning, and large-scale biological data to advance target discovery, disease understanding, biomarker development, and translational science. We are seeking a (Senior) ML Scientist with deep expertise in modern machine learning to lead the development and application of next-generation AI technologies for designing DNA and RNA sequences for nucleic acid-based medicines. We work closely with stakeholders in Cell Therapy, Gene Therapy, and Vaccine Oncology on diverse projects, ranging from platform development for lab-in-the-loop refinement of sequence designs to lead optimization for portfolio projects. Representative work includes designing regulatory elements to confer cell-type-specific transcription and engineering synonymous coding sequences to enhance translational efficiency. As a Scientist / Senior Scientist, you will directly lead sequence design campaigns, translating biological questions into predictive and generative models, and driving iterative sequence optimization in close collaboration with wet-lab experimentalists. The Opportunity Build, train, and fine-tune machine learning algorithms to optimize nucleic acid-based medicines for active portfolio projects Design candidate sequence libraries for lab-in-the-loop optimization cycles, analyze experimental readouts (e.g., MPRA, NGS), and iteratively update designs Collaborate cross-functionally with wet-lab scientists and project leads to understand therapeutic constraints and tailor design algorithms accordingly Present technical findings, candidate designs, and model performance metrics to cross-functional team members and stakeholders Stay current with advancements in biological sequence modeling and nucleic acid therapeutics to bring state-of-the-art methods into our pipeline Contribute to scientific publications Who You Are Ph.D. in a quantitative discipline (Bioinformatics, Computational Biology, Computer Science, Machine learning, or a related field) with 0-4 years of post-doctoral or industry experience Demonstrated research impact at the interface of machine learning and molecular biology, evidenced by publications in top-tier journals or ML conferences Strong Python programming skills and proficiency in deep learning frameworks such as PyTorch Hands-on experience developing, training, or fine-tuning sequence-to-function models for biological molecules (preferably DNA/RNA) Excellent communication skills in English, with the ability to speak to both computational and experimental scientists Preferred Qualifications Prior experience applying machine learning in a biotech, pharma, or industry setting Domain knowledge in nucleic acid-based therapeutics (e.g., mRNA design, AAV capsid/promoter engineering, cell therapy vectors) Experience with advanced ML frameworks relevant to sequence design, such as generative modeling (diffusion, autoregressive sequence models, masked language models), active learning, model interpretability, or uncertainty quantification Familiarity with high-throughput functional genomics data processing (e.g., MPRA, RNA-seq, ribosome profiling) About AI Biology & Translation (AIBT) AI Biology & Translation (AIBT) is part of the Computational Sciences Center of Excellence (CS-CoE). AIBT advances the development and application of cutting-edge artificial intelligence to accelerate biomedical discovery and translational science. By integrating expertise in machine learning, computational biology, and software engineering, AIBT develops AI capabilities that enable researchers to generate new biological insights, accelerate scientific decision-making, and transform research across Genentech & Roche. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Data Scientist Roche Digital Technology (RDT) is where innovation meets purpose. As a global team at the heart of Roche, we are a community of business-minded technologists committed to help shape tomorrow’s digital future of healthcare. Our mission is to power Roche through cutting-edge digital technologies, harnessing the potential of artificial intelligence, data, and scalable tech innovations. Driven by purpose and passion, we’re building a future where digital is a core strength across all of Roche, enabling smarter ways of working, unlocking human potential, and driving breakthroughs that truly matter for millions of patients around the world. You'll work alongside curious, ambitious technologists who value ownership, rigour, and fast, visible impact over process for its own sake. Rather than settling into one fixed lane, you'll move with the work as priorities shift, growing your expertise across a genuinely wide range of problems. If you want your day-to-day work to reach millions of patients and to help shape what a still-emerging technology looks like in practice, this is a rare moment to join at the ground floor. At Roche, we offer a hybrid work model that combines flexibility with in-person collaboration. For now, we require our employees to be in our Warsaw or Poznań office on average two days per week. The specific office days may vary depending on business needs, such as workshops, conferences, town halls, team meetings, and other collaborative events. The opportunity: Roche's AI Function builds the platforms, tools, and data science muscle that let teams across Roche turn AI, GenAI, and agentic ideas into real products, fast. We make it safe, simple, and scalable to build with LLMs, enterprise data, and orchestration, so experimentation stops staying experimental and starts driving real business value. And now we're pushing further into agentic AI: systems that reason, plan, and act on their own, under human oversight. Join us and help define how Roche builds, evaluates, and governs that next generation of AI at enterprise scale. The kind of work you'll do Build and ship Design and ship AI/ML solutions, from prototype to a monitored capability people actually depend on, including Roche's next generation of agentic AI: systems that plan and execute complex, multi-step work autonomously. Work closely with product owners, engineers, and business stakeholders throughout. Turn ambiguous problems into clear modelling approaches, and explain the trade-offs in language anyone can follow. Choose the right tool for the problem: a classical model, a fine-tuned model, retrieval over a foundation model or an agentic workflow, rather than reaching for an LLM by default. Write clean, production-ready, reproducible code, and help shape the reusable patterns the wider team relies on. Bring rigour Bring rigour to every experiment. Solid baselines, held-out testing, real error analysis. No shortcuts. Treat evaluation as core craft, not an afterthought. Build eval sets and harnesses for GenAI systems, use golden datasets and regression checks for prompts, and statistically evaluate outputs for safety, reliability and consistency, offline and in production. Root solutions in real user feedback, not just lab results. Measure and inform Power decisions with analytics. Surface the cost, value, adoption, and usage data that tells AI leadership what's working and where to invest next. Govern and share Build within Roche's governance, security, and compliance guardrails, from day one of a project to the last. Contribute to those guardrails in practice: help design the checks that help embed fairness, explainability and privacy into pipelines so they are enforced rather than aspirational. Share what you learn through reviews, demos, and onboarding docs. No lesson stays siloed. Who you are : Technical depth Hands-on expertise in data science and software engineering. Python, LLMs, RAG pipelines, agentic workflows. Equally comfortable writing production code, designing system architecture, or setting integration standards. Evaluate and fine-tune pre-trained models for domain use. Design RAG and search/synthesis architectures. Build evaluation harnesses and statistically evaluate outputs for safety, reliability, and consistency. Strong NLP foundations: preprocessing, language modelling, sentiment analysis, NER. A solid core in statistics, model evaluation, feature engineering and standard algorithms Real depth on vector embeddings, search theory, and vector database selection and architecture, along with prompt and context engineering. Strategic and operational range Comfortable moving from strategic roadmap planning to solving ad-hoc technical problems on the ground. Skilled at bridging non-technical stakeholders and technical implementation. Comfortable building MLOps/LLMOps pipelines for continuous deployment and monitoring, including observability for LLM systems (tracing, tokens, latency, cost telemetry and drift and hallucination monitoring). Comfortable forecasting and optimising infrastructure and API costs, and managing platform vendor relationships to keep tools interoperable, secure, and future-proof. Communication Strong written and verbal English, with the ability to explain technical trade-offs to technical and non-technical audiences alike. A learning posture that keeps pace with a fast-changing field, with enthusiasm for knowledge-sharing. Preferred/nice to have: Hands-on experience deploying enterprise AI solutions on AWS or Azure (GCP exposure a plus). Model risk management, fairness and bias mitigation, transparency, explainability, and data privacy. Pharma, healthcare, or financial services, including GxP compliance and handling sensitive information, plus awareness of emerging compliance standards for GenAI and foundation models. What You Get Salary Range: 170’100.00 - 243’000.00 - 315’900.00 PLN Annual based on an employment contract (Umowa o Pracę). Annual Performance Bonus: Target bonus of 15% based on performance. Dedicated Training Budget: Funding for certifications, AI/tech courses, global conferences, and diversified career paths. Recharge Fridays: 2 additional paid Fridays off per quarter available to completely disconnect. Take Time Program: Up to 3 months of sabbatical leave to use for any personal purpose. Flex Location: Freedom to work remotely from different global locations for specified periods throughout the year. Take Time for Charity: Up to 2 weeks of additional paid leave to engage in volunteering initiatives. Comprehensive Benefits: Private healthcare (LuxMed packages), group life insurance (UNUM), MultiSport card, and vacation subsidy. Stock & Tech Perks: Roche stock share purchase program, yearly sales of company laptops and cars, and much more! Apply directly and join us in shaping the future of healthcare. If you feel this offer suits a friend of yours, feel free to share it. Want to know what it’s like to be a part of Roche IT first-hand? Check out our blog! 👉 https://careers.roche.com/global/en/we-are-roche The controller of your personal data is Roche Polska Sp. z o.o., ul. Domaniewska 28, 02-672 Warsaw. The data is processed for the purpose of recruitment. You have the right to access your data, rectify it, delete it, limit processing, transfer it and - if processing is based on your consent - withdraw this consent at any time. Contact the Data Protection Officer at: Ochrona.danych@roche.com. More information on the principles of processing your personal data by Roche at the link: https://www.roche.pl/pl/content/klauzula-informacyjna-rekrutacja-en.html Roche Polska sp. z o.o. operates in full compliance with the law and does not tolerate any violations. Roche Polska sp. z o.o. has implemented a Procedure for Reporting Violations of Law. If you wish to report any irregularities related to our activities, all necessary information regarding the reporting process can be found on our website: https://www.roche.pl/kontakt/ochrona-sygnalistow-zglaszanie-naruszen . Compensation & Benefits The expected salary range for this position, based on the primary location of Warsaw Grafit is 170’100.00 PLN - 315’900.00 PLN. Final compensation will be determined by a number of factors, including your skills, experience, qualifications, and location. In addition to base pay, this role may be eligible for a discretionary annual bonus with a target of 15% subject to both individual and company performance. This position also offers an attractive benefits package . Learn more about how we reward our employees at Roche. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position As a Senior Data Scientist - Generative AI , you will join the Global Analytics and Technology Center of Excellence (GATE) in San José, Costa Rica . In this hands-on, high-impact role, you will design and deploy cutting-edge agentic capabilities and enterprise Generative AI applications. Moving seamlessly across the full product stack—from problem framing and data retrieval to multi-agent flow design, API development, and LLMOps evaluation—you will serve as a subject matter expert driving state-of-the-art AI architectures into production. The Opportunity Agentic Application Design: Architect end-to-end multi-agent applications, retrieval layer solutions, and foundational AI capabilities, taking ideas from prototype to production deployment. Advanced RAG & Retrieval: Build and optimize advanced Retrieval-Augmented Generation (RAG) pipelines, incorporating vector/graph databases, reranking algorithms, chunking strategies, and hybrid retrieval. Production-Grade Engineering: Write clean, tested Python code, manage APIs, enforce version control, and set up CI/CD pipelines for Generative AI systems. LLMOps & System Observability: Implement evaluation harnesses, prompt/version management, cost/latency optimization, and token economics monitoring for production agents. Strategic AI Consulting: Influence technical priorities across global enterprise stakeholders, evaluating when to deploy GenAI versus classical ML or deterministic engineering methods. Mentorship & Collaboration: Coach team members on agentic flow design and partner with Product Owners to align technical execution with user experience strategy. Who You Are Bachelor’s or Master’s degree in Computer Science, Data Science, AI/ML, or a related quantitative field. 7+ years of professional experience, with demonstrated hands-on expertise building enterprise Generative AI products and agentic workflows. Deep technical mastery of LLMs, vector databases, graph databases, reranking algorithms, and Agentic frameworks (LangChain, LangGraph, LlamaIndex, AWS AgentCore). Proven track record in RAG architecture design, chunking optimization, and retrieval quality evaluation. Solid software engineering skills in Python, SQL (and AI-generated SQL), API development, and MLOps/LLMOps monitoring platforms. Familiarity with agent protocols (MCP, A2A), multimodal AI applications, and frontend/UI tools (Figma, React, Angular) is advantageous. Must be currently based in Costa Rica or hold valid work authorization for San José. No relocation benefits are offered for this position. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position At Roche, we believe that every patient deserves the best possible care, supported by innovative science and technology. We are looking for a senior individual contributor to take significant technical ownership of components within our One Diagnostics Platform. In this role, you won't just build apps; you will design and develop the reusable Android components, frameworks, and libraries that power multiple medical diagnostics ecosystems. Your work will directly impact the reliability, security, and scale of software used globally in life-saving medical environments. Your responsibilities Design, develop and maintain shared Android applications, components, libraries and frameworks using Kotlin and Java. Develop clear, stable and well-documented APIs according to the Roche quality processes and regulatory requirements. Drive modular Android architecture and establish patterns that support scalability, maintainability and reuse. Ensure backward compatibility and manage the lifecycle, versioning and migration of shared components. Collaborate with project teams to understand common needs and translate them into reusable platform capabilities. Review technical designs and code, identify architectural risks and promote consistent engineering practices. Plan and perform software unit verification tests depending on the role as developer or development tester of a specific component from the One diagnostics Platform Develop robust automated tests, including unit, integration and UI tests where appropriate. Investigate complex technical issues affecting multiple applications and provide sustainable solutions rather than isolated fixes. Contribute to secure software design, protection of sensitive data and appropriate handling of application permissions according to regulatory guidelines. Create and maintain the technical documentation and development evidence required in a regulated medical environment. Work closely with product owners, system architects, quality, regulatory, cybersecurity and verification teams. Raise the Bar: Mentor other engineers through constructive code reviews, design discussions, and championing modern engineering practices. Who You Are You combine strong hands-on Android expertise with a systems-thinking mindset. You enjoy solving problems once and making the solution useful for many teams. You care about clear interfaces, maintainable code, reliable tests, and thorough documentation within a quality-driven, compliant environment. Requirements High proficiency in Kotlin and strong experience in Java . Extensive background in building Android applications, shared software components, system-level architecture, and Gradle build systems. Practical experience using AI-assisted tools within software development workflows. Proven track record designing modular architectures, managing APIs, and using versioning/dependency tools within highly regulated or safety-critical sectors (e.g., Medical Devices/MedTech, Automotive, Aviation, Defense, Railway). Strong grasp of the Android SDK, application lifecycles, memory management, clean architecture, and dependency injection. Solid experience with unit and integration test automation and pipeline integration (Azure DevOps/GitHub). Professional fluency in English (written and verbal). You are capable of traveling 5% to 10% of your time to different locations mainly within Europe. Beneficial Qualifications: Familiarity with healthcare/MedTech software regulatory standards (IEC 62304, ISO 13485, ISO 14971, IEC 81001-5-1). Experience with threat modeling, secure data handling, design controls, and regulatory submission documentation. What we offer The opportunity to build software that supports medical diagnostics and contributes to better healthcare. Significant technical ownership without requiring a people-management career path. Collaboration with experienced engineers and specialists across software, systems, quality, regulatory and cybersecurity. The opportunity to shape reusable technologies used across multiple products. A professional environment that values engineering quality, continuous learning and thoughtful technical decision-making. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position As a Senior Data Scientist - ML Engineering , you will join the Global Analytics and Technology Center of Excellence (GATE) in San José, Costa Rica . In this role, you will own the end-to-end path from machine learning models to scalable, reliable production systems supporting global Roche affiliates. Operating across the full MLOps and software engineering stack, you will architect cloud-native ML pipelines, build automated testing and CI/CD frameworks, instrument model observability, and set high software craftsmanship standards across the engineering team. The Opportunity ML Systems & Platform Engineering: Architect, deploy, and maintain end-to-end production ML services, training pipelines, containerization, and orchestration (Airflow/Dagster) with strict SLAs for performance and cost. MLOps Capability Building: Design reusable MLOps platform components including feature stores, model registries, experiment tracking, and automated CI/CD deployment pipelines using GitLab CI or GitHub Actions. Model Accuracy & Observability: Build automated back-testing frameworks and instrumentation for tracking data/concept drift, feature anomalies, and model performance decay, translating diagnostic findings into root-cause fixes. Cloud & Pipeline Automation: Implement cloud-native ML infrastructure across AWS, Azure, or GCP, systematically automating manual tasks and maintaining data synchronization contracts. Technical Leadership & Coaching: Establish engineering standards through code reviews, refactoring research code, and mentoring data scientists on production-grade software practices. Stakeholder Support: Partner with global affiliate teams to explain predictive model outputs, address business needs, and incorporate feedback into technical roadmaps. Who You Are Bachelor’s or Master’s degree in Computer Science, Data Science, Engineering, Statistics, or a quantitative discipline. 7+ years of relevant experience running and maintaining machine learning systems in production environments. Deep proficiency in Python, Linux/Bash, SQL, modern pipeline tools (Spark, dbt, Snowflake, Databricks), and clean API design. Hands-on expertise with containerization (Docker, Kubernetes), MLOps tools (MLflow, Weights & Biases), orchestration (Airflow), and CI/CD automation. Proven experience in cloud architectures (AWS, Azure, or GCP) and core ML frameworks (scikit-learn, XGBoost, PyTorch, TensorFlow, time-series forecasting). Strong analytical mindset focused on quality control, data contracts, and system observability (experience with LLMOps, streaming/Kafka, or GPU workloads is a plus). Must be currently based in Costa Rica or hold valid work authorization for San José. No relocation benefits are offered for this position. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position At Roche we are here to deliver better outcomes to more patients, faster. Our achievements help to transform the lives of millions of people. We’ve been supporting patients for over 100 years in the UK, building a reputation that we’re intensely proud of. Through this success, we’ve set an incredibly high standard. Those expectations continue to grow. The environment in which we operate changes at an ever-increasing pace. The industry is never going to stand still. As one united team at Roche UK, we know we need to boldly respond to these changes whilst keeping our customers and our patients at the heart of everything we do. So, we’re shooting for the stars, transforming ourselves into a much more open, dynamic, transparent, inclusive, collaborative and agile business. Purpose ● You will be responsible for the operational management of all key Pharmaceutical Quality Management System (QMS) processes and supporting the Qualified Persons in fullfiling their company and legal obligations. ● You will be responsible for maximising the potential of the pharmaceutical business by ensuring external and global GxP Quality requirements are translated simply into Roche policies & procedures. ● You will need to be adaptable to change and entrepreneurial in nature in order to identify opportunities, while maintaining a laser focus on ensuring compliance; therefore playing a key role in retaining Roche UK’s Licence to Operate. ● You will utilise skills and capabilities to work exibly as part of an empowered, self-managed, multi-skilled team to ensure Foundational and Squad-prioritised work is delivered in line with Organisational principles. ● You need to be authentic and self-accountable, a creative problem solver, a critical thinker and able to cultivate collaborative relationships across the organisation. This is a temporary position at Roche (initial 12 months) Career Opportunities ● You will use broad and comprehensive expertise within the GxP Quality environment to lead “Foundation work” and partner with the business to solve complex quality issues that impact the Chapter and/or wider business. ● You will complete "Foundational work" with continual review of ‘how’ it is done to drive efciency and minimise resources required to do it (without compromising on necessary standards). ● You will act as a guardian for high standards of compliance, ethics and safety; putting patients at the centre of all actions by consistent business behaviour that complies with applicable laws, industry codes and Roche’s Code of Conduct. ● You will collaborate with internal and external parties to anticipate trends and impact to QMS, mitigate GxP compliance risks, address gaps and enable the resolution of unique or unprecedented issues. ● You will own your development to ensure continuous skills and capabilities growth in line with your passion and the needs of the Organisation (present and future). Qualications and Experience ● Bachelor Degree in Science ● Experience of: o Working in a GxP Quality Assurance role providing quality and compliance expertise in support of Unplanned and Planned Events, CAPA management, Document management, and Quality Risk Management o Commercial and/or Clinical Batch Record review for product release o Health Authority Inspections ● Desirable Experience of: o Customer Complaints processing and management system o QMS key performance indicators trend analysis and management reporting o Internal and Supplier Auditing Who we are At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity. Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more . Besides extensive development and training opportunities, we offer exible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events. We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche. Roche is an Equal Opportunity Employer. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. The statements herein are intended to describe the general nature and level of work being performed by employees, and are not to be construed as an exhaustive list of responsibilities, duties, and skills required of personnel so classified. Furthermore, they do not establish a contract for employment and are subject to change at the discretion of Roche Products Ltd. At Roche Products we believe diversity drives innovation and we are committed to building a diverse and flexible working environment. All qualified applicants will receive consideration for employment without regard to race, religion or belief, sex, gender reassignment, sexual orientation, marriage and civil partnership, pregnancy and maternity, disability or age. We recognise the importance of flexible working and will review all applicants’ requests with care. At Roche difference is valued and we are proud to be an equal opportunity employer where you are encouraged to bring your whole self to work.